Chen Zhu's Team | Programming Strained Rings to Grow Multiple Functional Groups in One Step
In the world of chemistry, strained rings such as cyclopropanes and cyclobutanes behave like compressed springs, storing considerable reaction driving force. Yet a long‑standing problem has remained: after ring opening, reactions typically stop at the 1,3‑or 1,4‑difunctionalization stage, making it extremely difficult to continue “adding”functional groups on adjacent carbons.Now, a collaborative team led by Prof. Chen Zhu of Eastern Institute of Technology, Ningbo and Prof. Tao Shen of Shanghai
